Jan
30

Mammoth Biosciences aims to be Illumina for the gene editing generation

In 1998, the startup company Illumina launched a revolution in the life sciences industry by developing technology to slash the costs of identifying and mapping genetic material.

Now, a little over 20 years later, Mammoth Biosciences is hoping to do the same thing for gene editing tools.

The company, co-founded by Jennifer Doudna, who did some of the pioneering work to discover the gene editing enzyme known as CRISPR, has just raised $45 million as it looks to bring to market products that can be used not only for disease detection, but are more precise editing tools for genetic material.

Rather than get bogged down in the patent dispute that raged over the provenance and ownership of applications for the original CRISPR enzyme — the Cas9 discovered by Doudna and developed for clinical applications at the Broad Institute — Mammoth has joined a number of startups in identifying new enzymes with a broader array of properties.

“From the very beginning of the company we’ve only worked with novel new enzymes to create these diagnostic products and the new novel diagnostic and editing,” says Trevor Martin, Mammoth Biosciences co-founder and chief executive.

Chiefly, the company is touting its Cas14 enzyme, which the company says opens up new possibilities for programmable biology thanks to its small size, diverse targeting ability and high fidelity — meaning that there are no unforeseen side effects to edits made using the enzyme (something that has arisen with Cas9 applications).

“There’s not one protein that’s going to be the best at everything,” says Martin. “For any particular product that you’re building, at Mammoth, we have the broadest toolbox.”

The Cas14 enzyme can be used to make gene edits in-vivo, meaning in live organisms, instead of ex-vivo, or outside of an organism. The in-vivo use-case could accelerate the time it takes to conduct experiments or develop treatments.

“Twenty years from now, when the umpteenth drug gets approved using Crispr and some nuclease named Cas132013, people are going to look back on this patent battle and think, ‘what a godawful waste of money,’ ” Jacob Sherkow a patent law scholar at New York Law School told Wired back in 2018.

Already, Horizon Discovery, a Cambridge, U.K.-based gene editing technology developer, is using the new tools developed by Mammoth Bioscience to create new CRISPR tools for Chinese Hamster Ovary cell line editing.

That partnership is an example of how Mammoth is thinking about the commercialization of the new Cas14 enzyme line and its role in biological engineering.

“You will need a full toolbox of CRISPR proteins,” says Martin. “That will allow you to interact with biology in the same way that we interact with software and computers. “From first principles, companies will programmatically modify biology to cure a disease or decrease risk for a disease. That’s going to be really kind of a turning point.”

To achieve its vision, Mammoth has managed to nab top talent from the life sciences industry, including Peter Nell, a co-founder of Casebia (a joint venture between Bayer and CRISPR Therapeutics), who came on board as chief business officer, and Ted Tisch, a former executive at Synthego and Bio-Rad, who joined the company as chief operating officer.

The company also nabbed $45 million of funding, including investment firms Mayfield, NFX, Verily (the Alphabet subsidiary) and Brook Byers, which was led by Decheng Capital — bringing the company to more than $70 million in funding.

“There are a dozen or so products that are in clinical development with CRISPR,” says Ursheet Parikh, a partner with Mayfield. “Maybe that number would go up by five or 10 without Mammoth, but it will go up by one or two orders of magnitude with Mammoth.”

To Parikh, Mammoth is the best positioned of the CRISPR development tools, because the company is building a whole platform that customers can license and use to develop products using gene editing.

The thinking, according to Parikh, is as follows, “if this technology can power lots of applications, let’s basically ensure that lots of these applications can come to market and as that happens I get my app store cut.”

“It’s an Illumina-like business,” Parikh says. “Just as anybody who is innovating with genomics needs an Illumina sequencer because they want to be able to do the sequencing… if someone wants to do editing… This gives them the access to do the right sequencing.”

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Jan
30

IPO pricing for One Medical and Casper will set the tone for 2020’s unicorn debuts

Hello and welcome back to our regular morning look at private companies, public markets and the gray space in between.

As One Medical looks to become the first venture-backed company to price its IPO in 2020 this afternoon and Casper aims to price its own shares next Wednesday, the market is gearing up for a pair of tests.

If you listen to the Nasdaq and the NYSE, IPO volume in 2020 will prove vibrant. A surprise, perhaps, in the wake of the WeWork meltdown that many had expected might reduce IPO cadence. One Medical and Casper, though, are charging ahead, meaning that their debuts will help set the tone for the 2020 IPO market.

If they struggle with weak pricing and slow initial trading, their disappointing offerings could slow the IPO market. If they price well and are welcomed by the street, however, the opposite.

Let’s take a look at how many IPOs are coming, what One Medical and Casper are hoping for and what their results might mean for unicorn liquidity. Don’t forget that we’re still living in the midst of a unicorn liquidity crisis — there are hundreds of private companies worth $1 billion or more around the world that need an exist, and the market is creating them faster than it can get them out the door. If IPOs stumble in 2020, lots just won’t make it out before the market turns.

An IPO crowd

Yesterday, CNBC reported notes from Nasdaq CEO Adena Friedman and NYSE President Stacey Cunningham, each speaking about their expected IPO cadence in 2020. Friedman said there are “lot of companies looking to tap the public markets in the first half,” implying a strong flow of potential debuts.

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Jan
30

With $30 million in fresh funds, The Bouqs plans to plant its flower delivery business in Japan

The Bouqs plans to take a slice of Japan’s $6 billion flower market this year with a $30 million strategic growth round from Japanese enterprise business investor Yamasa. While The Bouqs still must compete with bigger contenders like 1-800-Flowers and FTD in the U.S., it will now have to take on incumbents like Ayoma Flower Market and FloraJapan, both of which also offer same-day delivery throughout the land of the rising sun.

So why Japan? According to The Bouqs founder and CEO John Tabis, his company had been looking to expand internationally for awhile and Japan seemed to fit well within that plan.

The Bouqs CEO and founder John Tabis

But as far as bigger competition in any country, Tabis is undeterred, telling TechCrunch there’s plenty of opportunities in the flower delivery business if you know where to look. “There’ve been four or five other startups that tried something similar — some of them no longer exist,” Tabis said. “But the thing that’s worked for us, the first is the way that we’ve sourced is unique and it’s really the foundation of our brand.”

The Bouqs sprung up in a wave of Silicon Valley funded flower delivery startups like BloomThat, Farm Girl and  Urban Stems, all promising Pinterest -worthy bouquets at the click of a button. But what set it apart was its farm-direct supply chain, cutting out costs from middlemen and delivering flowers that last longer.

This particular round now puts The Bouqs up top as far as total funding raised among its flower delivery startup peers, bringing in $74 million in total funding to date, with competitor Urban Stems in second place with $27 million in funding, according to Crunchbase.

Tabis also tells TechCrunch the new funds will further the company’s development into brick-and-mortar stores and that it’s jumping into the wedding biz. As anyone who’s ever planned a wedding will tell you, it’s an industry ripe for disruption — with brides and grooms spending about 8% of the budget on the flowers alone.

One other renewed focus for the company will be its subscription business, keeping customers set up with a fresh bunch of flowers once the old bouquet is ready for tossing. “It’s sort of the linchpin of our business that’s grown very nicely…expanding both our revenue and profitability,” Tabis told TechCrunch.

The SVP of Yamasa, Norikazu Sano, also mentioned further expansion into Asia for the company in a company press release, so we could see The Bouqs in more international areas over time, if all goes right in Japan.

“This financing will enable us to fully realize our vision to create a global network of top-quality farms paired with a category-defining local floral brand enabled by proprietary supply chain technology and vertically integrated sourcing capabilities. We’re so excited for this next phase of the business, and all of the opportunities that lie ahead,” Tabis said.

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Jan
30

One day left for early-bird tickets to TC Sessions: Robotics + AI 2020

No one ever wants to pay more, and that’s as true for well-financed companies as it is for early-stage startup founders on a shoe-string budget. So if you love robots and machine learning, why spend more on your ticket to TC Sessions: Robotics + AI 2020? Prices go up on January 31, which means you have just one day left to buy an early-bird ticket. You’ll save a tidy $150 in the process. Sweet!

On March 3, roughly 1,500 attendees will spend the day delving into the future of robots, the AI that drives them and the people at the forefront. We’re talking some of the top makers, visionaries, founders, investors and engineers. Join your community for live interviews, panel discussions, demos, workshops, audience/speaker Q&As and world-class networking.

We’ve posted the day’s agenda, and we’ll add a few more surprises in the coming weeks. Here’s a quick peek at just some of the engaging speakers and presentations you’ll enjoy:

Lending a Helping Robotic Hand: As populations age, caregivers in many countries are turning to robots for assistance. Vivian Chu, co-founder and CEO of Diligent Robotics, and Mike Dooley, co-founder and CEO of Labrador Systems, will join us to discuss the role technology can play in helping care for and assist those in need.Fostering the Next Generation of Robotics Startups: Robotics and AI are the future of many or most industries, but the barrier of entry is still difficult to surmount for many startups. Joshua Wilson, co-founder and CEO of Freedom Robotics, joins us to talk about how these companies are helping ease the first steps into the wider world of automation.

In a classic “but wait, there’s more” moment, our Pitch Night finalists will present live on the Main Stage. Don’t know what we’re talking about? Read more about Pitch Night here, and hey — we’re accepting applications until February 1. Don’t wait — toss your hat into the ring. It’s free, and you’ll have a chance to introduce your early-stage startup to a group of heavy-hitting influencers. What’s not to love?

TC Sessions: Robotics + AI 2020 takes place on March 3. You have plenty of time to plan the day, but your opportunity to save $150 runs out in one short day. Prices go up on January 31 — buy your early-bird ticket today.

Is your company interested in sponsoring or exhibiting at TC Sessions: Robotics + AI 2020? Contact our sponsorship sales team by filling out this form.

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Jan
30

SoftBank wants its on-demand portfolio to stop losing so much money

SoftBank wants its competing portfolio companies to stop losing so much money and, in some cases, to merge.

That’s the news out from Financial Times today, which reported that Uber and DoorDash discussed merging last year. The talks didn’t wind up in a deal.

The two companies, each heavily backed by SoftBank and its formerly active Vision Fund, compete in the food delivery space at great expense. Uber’s Eats business turned $392 million in adjusted net revenue in Q3 2019 into $316 million adjusted loss. That ocean of red ink actually makes DoorDash’s reported, projected $450 million 2019 operating loss look modest.

Perhaps by bringing the two companies together they would lose less money, and thus be in a better place to either return to their original IPO valuation or defend their existing private valuation.

Uber has famously struggled to retain value after its IPO, shedding worth during its public offering and since its debut. DoorDash, relatedly, was said to be in the market recently, but unable to close a new, large funding round. And as the two companies compete, a combination makes sense. Even more so when you consider their shared shareholder.

Other chaos

Uber and DoorDash aren’t the only examples of SoftBank-backed companies beating each other up with bricks of Vision Fund cash.

According to a report today in The Wall Street Journal, a fight in Latin America between several SoftBank-backed companies is raging:

Uber is under siege in Latin America amid a bruising price war where its ostensible rivals are Rappi and China’s Didi Chuxing Technology Co. But here’s the twist. All the combatants have as their biggest owner the same tech investor, Japan’s SoftBank Group Corp., which has injected a total of $20 billion into the three.

In the pre-unicorn era, you’ll recall the old venture maxim that no single group should invest in competing players. After all, why pay for one portfolio company to beat on another startup that you already helped finance? SoftBank, with its own investments and the Vision Fund, ignored that rule, and now it’s financing a fustercluck across the various American continents. (Though, there are some examples of other firms doing this, like Sequoia putting money into Uber and Didi.)

Which is why it might want DoorDash and Uber to link up. It might lessen one headache. Then SoftBank could work on figuring out how to keep Uber and Didi from beating each other up on rides in other markets, while disentangling Uber Eats and Rappi from a delivery scrap in yet more.

Perhaps SoftBank wants all the players to merge into a single, mega-delivery and ride corp. That would never pass regulatory oversight, of course, but at least it would centralize the losses and cash burn into a single income statement.

Think of the time it would save!

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Jan
30

SpaceX cautions on launch regulation that outpaces innovation

During the Federal Aviation Administration’s (FAA) 23rd annual Commercial Space Transportation Conference in Washington, D.C., one panel focused on the changing regulatory environment when it comes to private launch activities, and how those are integrated into existing rules and practices for managing commercial air transportation. Panelist Caryn Schenewerk, SpaceX senior counsel and senior director of space flight policy, emphasized that while the company always does the utmost to ensure safety in everything it does, the company also wants to focus on the actual state of the industry today and how it needs to grow as various partners work to establish new rules for the growing commercial launch sector.

“When aviation started, the Wright brothers weren’t flying over major populated cities,” Schenewerk pointed out. “They were outside Paris in an unpopulated field, and they were at Kitty Hawk on unpopulated beaches. And they were in Ohio in unpopulated areas.”

Schenewerk was directly addressing comments made by other panelists, and specifically ALPA Aviation Safety Chair Steve Jangelis, that suggested the emerging commercial launch industries may be looking far ahead to when they’re launching from spaceports located near populated areas, and launching with much more frequency than they are today. In general, Jangelis was advocating for laying the groundwork now for high levels of cooperation and integration between aviation traffic management and rocket launch operators.

Schenewerk was reluctant to concede any kind of direct equivalency between the commercial air transportation industry and the space launch sector, given their relative dissimilarity.

She noted that in terms of sheer volume, there’s a massive difference, with roughly 40 to 50 launches set for 2020 compared to millions of flights for commercial air. Airlines also use essentially the same small handful of airframes from suppliers like Boeing and Airbus, while each launch company has their own, very different vehicle with different conditions for launch and flight. Overall, she suggested then that anticipating some potential future state where the industries were more similar could result in stifling progress toward that ultimate goal.

“I hope we get to that million launches at some point, but when we are at that point, it’s going to be because we worked our way up the safety trajectory in a way that allows us to operate that way,” Schenewerk said. “Today, SpaceX can’t fly from a spaceport in the middle of the country, because we won’t get through the safety approval. We literally will not be licensed by the FAA to operate from that site, because we will then be flying over large populations of people — and we aren’t at that level of reliability and safety in this industry to fly over large populations of people with these kinds of rockets. Could we get there someday? Yeah, we can get there someday when we’ve had a million flights, and a million prove-outs of our capability, when we have such repeatability that we’re in that level.”

Ultimately, Schenewerk’s comments and Jangelis’ responses illustrate that there are still a lot of places where younger companies and emerging technologies like reusable rocket launches are conflicting with the views of more established industries and players operating in some shared spaces.

FAA Administrator Steve Dickson also addressed the agency’s ongoing work to establish launch rules, which were released as a draft last year and which Dickson said will likely be finalized sometime this fall, once the FAA has incorporated industry comments and feedback.

“Let’s think about that big vision, that big day when lots of things are happening,” Schenewerk said. “But let’s also not yell at our kid for not being able to fly an airplane when they can barely walk — and I think that’s where we are right now: We’re still figuring out how to walk and run in this industry.”

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Jan
30

How acquirers look at your company

Ed Byrne Contributor
Ed Byrne is an entrepreneur, investor and co-founder of Scaleworks.

There comes a time for many founders when they are ready to pass the baton of running their business to someone else. It’s a rare founder who wants to go from zero to running and scaling a large, long-term company. When that time comes — you may have expectations on what you would like to exit for, or have read stories about other company valuations — I thought it might be useful to share some of the other side’s viewpoint. So, here are some of the criteria we use at Scaleworks when evaluating a new opportunity.

Rule 1: Don’t lose money

The cliche is “rule number two: read rule number one.” Make sure any acquisition you consider is at a fair price and that you have identified some low-hanging fruit opportunities for improvement that you are confident in your ability to execute on.

What does a fair price mean?

For us, it means a price we have confidence we can either pay back over time from cash flow, or sell the business on a profit multiple for at least the same price we bought it for.

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Jan
30

CloudTrucks raises $6.1 million to help truckers run their businesses

After selling autonomous driving startup Scotty Labs to DoorDash just five months ago, entrepreneur Tobenna Arodiogbu is back with a new startup. This time, he’s focused solely on truck drivers and their businesses. CloudTrucks, which aims to help truck drivers earn more money, has closed a $6.1 million round led by Craft Ventures with participation from Khosla Ventures, Kindred Ventures and Abstract Ventures.

Described as a “business in a box,” CloudTrucks is designed to make it easier for truck owners and operators to run their businesses. Through software and data science, CloudTrucks aims to reduce operating costs for truck drivers and improve revenue, cash-flow and costs.

In the U.S., about 91% of fleets are small businesses, operating six or fewer trucks, according to the American Trucking Associations. Last year, almost 800 trucking businesses went bankrupt in the U.S. Analysts attribute that to a rise in insurance costs and excess supply, which drove shipping rates down. Additionally, operators are tasked with managing safety programs, invoicing and other paperwork. This is where CloudTrucks comes in.

“CloudTrucks focuses on the owner-operator and small trucking companies because they are the lifeblood of the industry and facing the largest pressures with fast-rising insurance rates, predatory factoring options and a quickly changing landscape,” Arodiogbu told TechCrunch.

Already, CloudTrucks has a small number of early customers to fine-tune the platform. The startup is accepting new customers on a case-by-case basis.

Prior to CloudTrucks, Arodiogbu co-founded Scotty Labs to enable humans to virtually control cars and trucks. The idea was to assist drivers in long-haul trips. Before DoorDash’s acquisition of the startup, Scotty Labs had raised $6 million in funding. Now, Arodiogbu serves as an advisor to DoorDash.

“Tobenna is a proven entrepreneur and product thinker with a clear vision of the problem CloudTrucks intends to solve,” Craft co-founder and general partner David Sacks said in a statement to TechCrunch. “Trucking is at the heart of the American economy and yet technology still plays a very small role. We are excited to support the entire CloudTrucks team as they build the platform that will increase revenue and efficiency for thousands of owner-operator truck drivers.”

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Jan
30

470th Roundtable For Entrepreneurs Starting NOW: Live Tweeting By @1Mby1M - Sramana Mitra

Today’s 470th FREE online 1Mby1M Roundtable For Entrepreneurs is starting NOW, on Thursday, January 30, at 8 a.m. PST/11 a.m. EST/5 p.m. CET/9:30 p.m. India IST. Click here to join. PASSWORD:...

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Original author: Maureen Kelly

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Jan
30

1Mby1M Virtual Accelerator Investor Forum: With Jishnu Battacharjee of Nexus Venture Partners (Part 4) - Sramana Mitra

Jishnu Battacharjee: There are two core principles for Unacademy. One is that the educator can build the content easily. The second is, the content is bite-sized. The idea was, you can talk about a...

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Original author: Sramana Mitra

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Jan
30

The don’ts of debt for fast-growing startups

Roger Hurwitz Contributor
Roger Hurwitz is a founding partner at Volition Capital. He focuses primarily on investments in software and technology-enabled business services.

I work every day with company founders who are grappling with the challenges of driving business growth while keeping their finances on an even keel. One topic we often discuss is how to take advantage of debt to drive business growth — without it turning into a problem.

In my experience, debt can serve as a valuable piece of a company’s capital structure. The key is to use debt for the right purposes and to understand the implications of doing so. For example, short-term loans (one to two-year terms) are useful for financing receivables and inventory to help manage cash flow. These working capital facilities have attractive interest rates (often in the 5% range) and are well understood by the lending community.

By contrast, mezzanine loans (usually three to five-year terms) are better suited to provide the flexibility and runway needed to prove out certain initiatives prior to securing an equity investment or a liquidity event. These loans tend to have limited covenants, are not secured by specific working capital assets and are junior to the working capital loans. Given their higher-risk profile, they are more expensive than short-term loans, with lenders typically targeting a return of 15% to 20%, split between a current pay interest rate of 10%+ and expected stock appreciation from the receipt of warrant coverage.

Regardless of the type of debt a company takes on, there are certain principles to consider to keep the debt from threatening the success of the business. Should you decide to take on debt, understand the implications and consider the following five rules:

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Jan
30

470th Roundtable For Entrepreneurs Starting In 30 Minutes: Live Tweeting By @1Mby1M - Sramana Mitra

Today’s 470th FREE online 1Mby1M Roundtable For Entrepreneurs is starting in 30 minutes, on Thursday, January 30 at 8 a.m. PST/11 a.m. EST/5 p.m. CET/9:30 p.m. India IST. Click here to join....

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Original author: Maureen Kelly

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Jan
30

Medloop secures €6M from Kamet Ventures and AXA for self-service patient app

Medloop, which allows patients to manage healthcare needs and providers, has secured €6 million from Kamet Ventures and AXA.

The cash will be used to enhance its product offering and continue expansion across Germany and the U.K. Medloop is also developing an evidence-based medical rule engine embedded on the Electronic Medical Record (EMR) of patients.

Medloop offers patients what it calls “intuitive” self-service features in an app that enables them to navigate their own healthcare, including online appointment bookings, electronic medical results and prescription refills, as well as chatting in-app with healthcare providers.

Founded in 2018 by Berlin-based entrepreneur Shishir Singhee, some medical practices in Germany use the Medloop doctor system to run their entire practice, using it to give an overview of their patient population.

Singhee, said: “Healthcare today has become increasingly impersonalized as ever-growing patient registers have made it challenging for doctors to treat patients in a bespoke way. Medloop strives to bridge this critical gap, by employing technology to empower patients and help doctors deliver proactive and holistic care.“

Stephane Guinet, CEO of Kamet Ventures, said: “It is no secret how overstretched doctors are in terms of the time and care they can offer each patient. Medloop’s offering is a novel solution to this challenge and we are very excited to be part of Medloop’s growth story given how critical its offering is to the U.K. market and beyond.”

Medloop achieved compatibility with EMIS last summer, enabling its entry into the U.K. market.

In Germany, its main competitors are the incumbents that were built in the early 1990s, such as Medatix and Medistar. In the U.K. it is up against patient management tools such as QMasters.

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Jan
30

Apple Rides High on iPhones, Wearables, Services - Sramana Mitra

Apple (Nasdaq: AAPL) announced its first quarter results that put all iPhone doubters to rest. The holiday quarter saw iPhones sales surge to record high levels. With the continuing 5G revolution...

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Original author: MitraSramana

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Jan
30

Massachusetts Global Entrepreneur In Residence Five Year Results

I continue to be a strong supporter of legal immigration to the United States. A fundamental belief of mine is that entrepreneurs should be able to start their companies anywhere they want. A corollary to that is some of the historical success of the US as an entrepreneurial ecosystem has been being the place that entrepreneurs want to start a company.

Today, it’s hard to get a visa to start a company in the US. Our legal immigration system is complex and expensive to navigate, and there are few choices for entrepreneurs, especially aspiring entrepreneurs, who haven’t already managed to get a visa.

For the past five years, I’m been involved in an effort called the Global EIR program. It’s a national effort, led by Craig Montuori, that is modeled after an extremely successful program in Massachusetts, led by William Brah at the University of Massachusetts. The roadmap for starting a company on a visa is now well defined.

The results in Massachusetts have been extraordinary. Over the past five years, As of today, 66 Initial H-1B visas have been approved with 100% visa success rate. The companies founded by these entrepreneurs employ 940 people and have raised over $500 million in venture capital.

Imagine if we had this level of activity in all 50 states?

Original author: Brad Feld

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Jan
30

All eyes are on the next liquidity event when it comes to space startups

At the FAA’s 23rd Annual Commercial Commercial Space Transportation Conference in Washington, DC on Wednesday, a panel dedicated to the topic of trends in VC around space startups touched on public vs. private funding, the right kinds of space companies that should even be considering venture funding, and, perhaps most notably, the big L: Liquidity.

Moderator Tess Hatch, Vice President at Bessemer Venture Partners, addressed the topic in response to an audience question that noted while we’ve heard a lot about how much money will flow into space-related startups from the VC community, we haven’t actually et seen much in the way of liquidity events that prove out the validity of these investments.

“In 2008, a company called Skybox was created and a handful of years later Google acquired the company for $500 million,” Hatch said. “Every venture capitalist’s ears perked up and they thought ‘Hey, that’s pretty good ROI in a short amount of time – maybe the space thing is an investable area’ and then a ton of venture capital investments flooded into space startups, and all of these venture capitalists made one, or maybe two investments in the area. Since then, there have not been many — if any – liquidity events: Perhaps Virgin Galactic going public via the SPAC (special uprose vehicle) on the New York Stock Exchange late last year would be the second. So we’re still waiting; we’re still waiting for those exits, we are still waiting for companies to pave the path for the 400+ startups in the ecosystem to return our investment.”

Hatch added that she’s looking at a number of companies who have the potential to break this somewhat prolonged exit drought in 2020, including five who are either quite mature in terms of their development, naming SpaceX, Rocket Lab, Planet and Spire as all likely candidates to have some kind of liquidity event in 2020, with the mostly likely being an IPO.

Space as an industry was described to me recently as a ‘maturing’ startup market by Space Angels CEO Chad Anderson, by virtue of the distribution of activity in terms of the overall investment rounds in the sector. There is indeed a lot of activity with early stage companies and seed rounds, but the fact remains that there hasn’t been much in the way of exits, and it’s also worth pointing out that corporate VCs haven’t been as acquisitive in space as some of their consumer and enterprise technology counterparts.

The panel touched on a lot more apart from liquidity, which actually only came up towards the end of the discussion, which included panelists Astranis CEO and co-founder John Gedmark; Capella Space CEO and founder Payam Banazadeh and Rocket Lab VP of Global Commercial Launch Services Shane Fleming. Both Gedmark and Banazadeh addressed aspects of the risks and benefits of seeking VC as a space technology company.

“Not every space business is a venture-backable business,” said Banazadeh earlier in the conversation. “But there are a lot of space businesses that are specifically going after raising venture money, and that’s dangerous for everyone – because at the end of the day venture is looking at high risk, high return. The ‘high return’ comes from being able to get substantial amount of revenue in a market that’s big
enough for those revenues to be coming from. But if your idea is to go build, maybe, some very specific part in a satellite, then you have to make the case of why you’ll be able to make those returns for the investors, and in a lot of cases, that’s just not possible.”

Banazadeh also concedes that doing any kind of space technology development is expensive, and the money has to come from somewhere. Gedmark talked about one popular source, government funding and grants, and why that often isn’t as obviously a positive thing for startups as it might seem.

“Small government grants can be great, and obviously a fantastic source of non dilutive capital,” Gedmark said. “But there is a little bit of a trick there, or something to be aware of: I think people are often surprised how much time is spent in the early days of a startup refining the exact idea and the product, and if you’re not certain that you have the that product market fit […] then, the government grant can be extremely dangerous, because they will fund you to do something that is sort of similar to what to what you’re doing, but it really prevents you changing your approach later; you’re going to end up spending time executing on the specific project of the program manager on the government side and you’re executing on what they want.”

VC funds, on the other hand, come with the built-in expectation that you’re going to refine and potentially even change direction altogether, Gedmark says. Depending on the terms of the public funding you’re seeking, that flexibility may not be part of the arrangement, which ultimately could be more important than a bit of equity dilution.

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Jan
29

UCSD hospital gets a drone delivery program powered by Matternet and UPS

Drone delivery may not make a lot of sense for food or parcel delivery yet, but for hospitals it could be a lifesaver. A new test program is being inaugurated at UC San Diego’s Jacobs Medical Center, where Matternet drones operated by UPS will fly blood samples and other items to and from other nearby facilities.

The new program will be the third under Matternet’s belt; an earlier partnership with UPS has made some 1,900 flights at WakeMed hospital in North Carolina, and flights with SwissPost in Zurich resume this month after crashes put them on ice over the summer.

Biological samples and other items that need to be moved quickly generally travel by courier service, which is of course fine sometimes, but not during rush hour. No one wants to have a second spinal tap because the first one got stuck in traffic.

The flights these drones will be undertaking will be autonomous, but with remote monitoring and line of sight from Jacobs to the Moores Cancer Center and Center for Advanced Laboratory Medicine, both of which are less than a mile away.

It’s a big month for Matternet, which in addition to these two concurrent flight test programs recently pulled in a strategic round from the healthcare-focused McKesson Ventures.

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Oct
06

StreamElements pushing forward in the diversity space with its latest creator program

Fifty iPads were stolen from Verkada co-founder Hans Robertson’s old company. Only when they checked the security system did they realize the video cameras hadn’t been working for months. He was pissed. “The market lagged behind the progress seen in the consumer space, where someone could buy high-end cameras with cloud-based software to protect their home,” Verkada’s CEO and co-founder Filip Kaliszan tells me of his own attempt to buy enterprise-grade security hardware.

Usually, startups ascend on the backs of fresh technologies and developer platforms. But Kaliszan and Robertson realized that commercial security was so backward that just implementing the established principles of machine vision and the cloud could create a huge company. The plan was to keep data secure yet accessible and train its cameras to take clearer photos when AI detects suspicious situations instead of just grainy video.

At first, few could see the vision through the slow upgrade cycles and basement security rooms common with most potential clients. “The seed and the A were extremely difficult rounds to raise compared to the later rounds because people didn’t believe we could execute what were are proposing,” Kaliszan glumly recalls.

But today Verkada receives a huge vote of confidence. It just raised an $80 million Series C at a stunning $1.6 billion post-money valuation thanks to lead investor Felicis Ventures writing Verkada its biggest check to date. The cash brings Verkada to $139 million in funding to sell dome cameras, fisheye lenses, footage viewing stations and the software to monitor it all from anywhere.

Why sink in so much cash at a valuation triple that of Verkada’s $540 million price tag after its April 2019 Series B? Because Verkada wants to bring two-factor authentication to doors with its new access control system that it’s announcing is now in beta testing ahead of a Spring launch. Instead of just allowing a stealable key fob or badge to open your office entryway, it could ask you to look into a Verkada camera too so it can match your face to your permissions.

“Our mission is to be the essential physical security software layer for every building, and the foundation of a larger enterprise IoT infrastructure,” Kaliszan tells me. By uniting security cameras and door locks in one system, it could keep banks, schools, hospitals, government buildings and businesses safe while offering new insights on how their spaces are used.

The founders’ pedigrees don’t hurt its efforts to sell that future to investors like Next47, Sequoia Capital and Meritech Capital, which joined the round. Robertson co-founded IT startup Meraki and sold it to Cisco for $1.2 billion. Kaliszan and his other co-founders Benjamin Bercovitz and James Ren started CourseRank for education software while at Stanford before selling it to Chegg.

Making a better product than what’s out there isn’t rocket science, though. Many building security systems only let footage be accessed from a control room in the building… which doesn’t help much if everyone’s trying to escape due to emergency or if a manager elsewhere simply wants to take a look. Verkada’s cloud lets the right employees keep watch from mobile, and data is also stored locally on the cameras so they keep recording even if the internet cuts out. “Our competitors stream unencrypted video and it’s on you to protect it. We’re responsible for handling that data,” Kaliszan says.

Verkada’s machine vision software can make sense of all the footage its cameras collect. “We can immediately show them all the video containing a particular person of interest rather than manually searching through hours of footage,” Kaliszan insists. “Our platform can use AI/machine learning to recognize patterns and behaviors that are out of the norm in real time.”

For example, a hostage negotiator was able to use Verkada’s system to assess whether a SWAT team needed to invade a building. Verkada can group all spottings of an individual together for review, or scan all the footage for people wearing a certain color or with other search filters.

Indeed, 2,500 clients, including 25 Fortune 500 companies, are already using Verkada. In the last year it has tripled revenue, partnered with 1,100 resellers, launched nine new camera models, added people and vehicle analytics, opened its first London office and is on track to grow from 300 to 800 employees by the end of 2020.

“We call this reinvention,” says Felicis Ventures founder and managing director Aydin Senkut. “One thing people underestimate is how big this market is. Honeywell is valued at $110 billion-plus. There’s a Chinese company that’s over $50 billion. The opportunity to be the operating system for all buildings in the world? Sounds like that market couldn’t be better.” Senkut knows Verkada works because he had it installed in all his homes and offices.

Most enterprise software companies don’t have to worry about the complexities of hardware supply chains. There’s always a risk that its sales process stumbles, leaving it stuck with too many cameras. “We’re still burning money. We’re not there yet or we wouldn’t be raising venture. Because we’re going after a mature market, you can’t come at it with a model that doesn’t make sense. Investors come at it from a hard-nosed approach,” Robertson admits.

“People have a tendency to write off Verkada as a boring camera company. They don’t realize how access control as the second product is going to supercharge the company’s potential,” Senkut declares.

One bullet Verkada dodged is the one firmly lodged in Amazon’s chest. Ring security cameras have received stern criticism over Amazon’s cooperation with law enforcement that some see as a violation of privacy and expansion of a police state. “We don’t have any arrangements with law enforcement like Ring,” Kaliszan tells me. “We view ourselves as providing great physical security tools to the people that run schools, hospitals and businesses. The data that those organizations gather is their own.”

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Oct
09

PDQ.com acquires SimpleMDM, moves into Apple device management 

“We’re trying to shift cryptocurrency from this speculative asset class to driving real-world utility,” Coinbase CEO Brian Armstrong tells me. How? Through commerce and micropayments. But now Coinbase has the who to build it. Today the startup announced it has hired away former head of Product for Indian e-commerce giant Flipkart and Google Shopping VP of Product Surojit Chatterjee to become Coinbase’s chief product officer.

“I’ve always enjoyed being associated with technology that is on the brink of changing how we live” writes Chatterjee. “Google ads has helped democratize commerce, Flipkart and ecommerce has revolutionized life in India, and I believe Coinbase is going to turn conventional finance on its head.”

Chatterjee spent more than 11 years at Google over two stints, the first as a founding member of Google’s mobile search Ads product that’s grown to tens of billions in revenue per year. When he starts at Coinbase next week, Armstrong tells me he’ll help Coinbase organize its complex array of products, including its cryptocurrency exchange, wallet, stablecoin, incentivized crypto education platform Earn and Coinbase Commerce that lets businesses take payments in Bitcoin, Ethereum and more. Chatterjee replaces Jeremy Henrickson, the former Coinbase CPO who departed in December 2018.

“Surojit is a huge asset here because we’re a product-led company,” Armstrong says. “We have different leaders and they increasingly have responsibilities around P&L. Having one really experienced chief product officer that can mentor them and teach them to own revenues and budgets — really in the model of Google — that will professionalize Coinbase.”

One opportunity Armstrong hopes Chatterjee can help Coinbase seize on is building products for emerging markets where financial infrastructure is weak. “E-commerce is not equally distributed around the world. Micropayments don’t work that well … Him spending time living in India, a developing market, he deeply understands mobile money.” Given the explosion of phone-based payments, the demonetization and the prevalence of cash on delivery methods in India that Flipkart dealt with, “his background is kind of ideal from that worldly perspective,” Armstrong explains.

Chatterjee cites his upbringing as inspiration to deliver “economic freedom for everyone,” as Armstrong says is Coinbase’s mission. “Growing up in India in a poor middle-class household, I saw very closely what a lack of liquid cash does to a family’s lifestyle,” Chatterjee recalls. 

“As a kid I would go with my mom to a local bank to withdraw money. And believe me when I tell you that the process was epic!” It included withdrawal slips, tokens and anxiously trying to match current signatures to versions decades old. When India demonetized and made everyone exchange their cash, “My dad, who was almost 80 at that time, stood in a queue for five hours to get 2000 Rs, which was the per-day limit for the first week. That’s less than $30!” Digital money could ensure people always have access to everything they own.

Surojit Chatterjee (far right) rides along for a Flipkart delivery to understand the consumer commerce experience

In developed countries, Armstrong sees a chance for Chatterjee to enable digital content creators to turn their passion into their profession. “There’s lots of people who lurk on Reddit or Stack Overflow and answer questions … If there was real money on these things, these could be their full time jobs — contributing content on user-generated social sites,” Armstrong predicts. “I think you’d see a lot more contributions, as well.”

Now might be the perfect time to hire Chatterjee since we’re in a lull period for cryptocurrency in the wake of the rush at the end of 2018. “Crypto is always challenging to navigate. In these periods when it’s relatively quiet, we tend to do really well,” Armstrong says. The company grew market share, volume and app installs versus competitors between 50% and 100%, according to the CEO. Referencing ancient war strategy, Armstrong concludes that, “There’s years where you just want to train the soldiers and stockpile resources and you’re basically just preparing. We’re building the company, not just responding to crazy hype.”

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Oct
09

Security.org: 68% of Americans use the same password across accounts

Just two days stand between you and serious savings on tickets to TC Sessions: Robotics + AI 2020. This annual day-long event draws the most innovative and visionary technologists, researchers and investors from two game-changing industries — last year we hosted 1,500 attendees. Make a smart investment. Buy an early-bird ticket before prices go up on January 31 and save $150.

Looking for exposure? We have two fantastic ways to put your early-stage startup in front of a highly influential group of VCs and technologists. Check this out.

Apply to compete in Pitch Night. Ten startups will compete in a mini pitch-off at a private event the night before the conference. A panel of VC judges will choose five finalists to pitch again the next day from the TC Sessions Main Stage. All 10 teams will each receive two free tickets to the event. Submit your application here by February 1. We’ll notify selected startups by February 15.

Buy a Startup Exhibitor Package and demo at the event. You’d better jump on this opportunity, and fast — we have only two packages left. The $2,200 price includes four tickets to the event. Bring your crew and quadruple your networking potential.

Now let’s talk about the kind of programming you can expect. We’re talking a full day of presentations, panel discussions, world-class speakers, workshops, robot demos and plenty of time for networking. Here’s a sample of what’s on tap (you can check out the day’s agenda here):

The Next Century of Robo-Exoticism: In 1920, Karl Capek coined the term “robot” in a play about mechanical workers organizing a rebellion to defeat their human overlords. Join expert panelists Abigail De Kosnik (Center for New Media, University of California, Berkeley), David Ewing Duncan (Arc Fusion), Ken Goldberg (UC Berkeley College of Engineering) and Mark Pauline (Survival Research) as they discuss cultural views of robots in the context of “Robo-Exoticism,” which exaggerates both negative and positive attributes and reinforces old fears, fantasies and stereotypes.A Live Demo from the Stanford Robotics Club — because everybody loves to see robots in action.Opening the Black Box with Explainable AI: Machine learning and AI models can be found in nearly every aspect of society today, but their inner workings are often as much a mystery to their creators as to those who use them. UC Berkeley’s Trevor Darrell, Krishna Gade of Fiddler Labs and Karen Myers from SRI International will discuss what we’re doing about it and what still needs to be done.

TC Sessions: Robotics + AI 2020 takes place on March 3, but early-bird tickets disappear in just two days. Remember the deadline: January 31. Get the most out of your startup dollars — buy a ticket now and save $150.

Is your company interested in sponsoring or exhibiting at TC Sessions: Robotics + AI 2020? Contact our sponsorship sales team by filling out this form.

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