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After TechCrunch broke the news yesterday that Coursera was planning to file its S-1 today, the edtech company officially dropped the document Friday evening.

Coursera was last valued at $2.4 billion by the private markets, when it most recently raised a Series F round in October 2020 that was worth $130 million.

Coursera’s S-1 filing offers a glimpse into the finances of how an edtech company, accelerated by the pandemic, performed over the past year. It paints a picture of growth, albeit one that came at steep expense.

Revenue

In 2020, Coursera saw $293.5 million in revenue. That’s a roughly 59% increase from the year prior when the company recorded $184.4 million in top line. During that same period, Coursera posted a net loss of nearly $67 million, up 46% from the previous year’s $46.7 million net deficit.

Notably the company had roughly the same noncash, share-based compensation expenses in both years. Even if we allow the company to judge its profitability on an adjusted EBITDA basis, Coursera’s losses still rose from 2019 to 2020, expanding from $26.9 million to $39.8 million.

To understand the difference between net losses and adjusted losses it’s worth unpacking the EBITDA acronym. Standing for “earnings before interest, taxes, depreciation and amortization,” EBITDA strips out some nonoperating costs to give investors a possible better picture of the continuing health of a business, without getting caught up in accounting nuance. Adjusted EBITDA takes the concept one step further, also removing the noncash cost of share-based compensation, and in an even more cheeky move, in this case also deducts “payroll tax expense related to stock-based activities” as well.

For our purposes, even when we grade Coursera’s profitability on a very polite curve it still winds up generating stiff losses. Indeed, the company’s adjusted EBITDA as a percentage of revenue — a way of determining profitability in contrast to revenue — barely improved from a 2019 result of -15% to -14% in 2020.

There’s more AI news out there than anyone can possibly keep up with. But you can stay tolerably up to date on the most interesting developments with this column, which collects AI and machine learning advancements from around the world and explains why they might be important to tech, startups or civilization.

To begin on a lighthearted note: The ways researchers find to apply machine learning to the arts are always interesting — though not always practical. A team from the University of Washington wanted to see if a computer vision system could learn to tell what is being played on a piano just from an overhead view of the keys and the player’s hands.

Audeo, the system trained by Eli Shlizerman, Kun Su and Xiulong Liu, watches video of piano playing and first extracts a piano-roll-like simple sequence of key presses. Then it adds expression in the form of length and strength of the presses, and lastly polishes it up for input into a MIDI synthesizer for output. The results are a little loose but definitely recognizable.

“To create music that sounds like it could be played in a musical performance was previously believed to be impossible,” said Shlizerman. “An algorithm needs to figure out the cues, or ‘features,’ in the video frames that are related to generating music, and it needs to ‘imagine’ the sound that’s happening in between the video frames. It requires a system that is both precise and imaginative. The fact that we achieved music that sounded pretty good was a surprise.”

Another from the field of arts and letters is this extremely fascinating research into computational unfolding of ancient letters too delicate to handle. The MIT team was looking at “locked” letters from the 17th century that are so intricately folded and sealed that to remove the letter and flatten it might permanently damage them. Their approach was to X-ray the letters and set a new, advanced algorithm to work deciphering the resulting imagery.

“The algorithm ends up doing an impressive job at separating the layers of paper, despite their extreme thinness and tiny gaps between them, sometimes less than the resolution of the scan,” MIT’s Erik Demaine said. “We weren’t sure it would be possible.” The work may be applicable to many kinds of documents that are difficult for simple X-ray techniques to unravel. It’s a bit of a stretch to categorize this as “machine learning,” but it was too interesting not to include. Read the full paper at Nature Communications.

You arrive at a charge point for your electric car and find it to be out of service. You might even leave a bad review online. In fact, thousands of such reviews exist and constitute a potentially very useful map for municipalities looking to expand electric vehicle infrastructure.

Georgia Tech’s Omar Asensio trained a natural language processing model on such reviews and it soon became an expert at parsing them by the thousands and squeezing out insights like where outages were common, comparative cost and other factors.

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In the world of early-stage startups, job titles are often a formality. In reality, each employee may handle a dozen responsibilities outside their job description. The choose-your-own-adventure type of work style is part of the magic of startups and often why generalists thrive here.

However, as a company progresses and the team grows, there comes a time when a founder needs to carve out dedicated roles. Of these positions, product management might be one of the most elusive — and key — roles to fill.

We spoke to startup founders and operators to get their thoughts about how and when they hired their first product manager. Some of the things we talked about were:

 Which traits to look for. Why it’s important to define the role before you look for your best fit. Whether your new hire needs to have a technical background. The best questions to ask in an interview. How to time your first hire and avoid overhiring.

Don’t hire for the CEO of a product

Let’s start by working backward. Product managers often graduate into a CEO role or leave a company to become a founder. Like founders, talented product managers have innate leadership skills and are able to effectively and clearly communicate. Similarly, both roles require a person who is a visionary when it comes to the product and execution.

David Blake was a product manager before he became a serial edtech founder who created Degreed, Learn In, and most recently, BookClub. He says that experience helped him launch the first prototype of Degreed and attract first clients.

“The must-have skill is the ability to put the team’s best wisdom in check and inform the product decisions with users and potential clients to inform what you are building,” he said. The person “must also be able to take the team’s mission and develop and sell that narrative to users and potential clients. That is how you blaze a new trail, balance risk, while avoiding building a ‘faster horse.”

The overlapping synergies between PMs and founders is part of the reason why the role is so confusing to define and hire for. Ken Norton, former director of product at Figma who recently left to solo advise and coach product managers, says companies can start by defining what PMs are not: The CEO of the product.

“It’s about not handing off the product responsibilities to somebody,” he said. “You want the founder and the CEO to continue to be the evangelist and visionary.” Instead, the role is more about day to day “blocking and tackling.” Norton wrote a piece more than 15 years ago about how to hire a product manager, and it’s still an essential read for anyone interested in the field.

Define the role and set your expectations

Product managers help translate all the jugglers within a startup to each other; connecting the engineer with marketing, design with business development and sales with all the above. The role at its core is hard to define, but at the same time is the necessary plumbing for any startup that wants to be high-growth and ambitious.

While a successful product manager is a strong generalist, they have to have the ability to understand and humanize technical processes. The best candidates, then, have some sort of technical experience as an engineer or otherwise.

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Optimizely co-founder Dan Siroker said the idea for his new startup Scribe goes back to a couple of personal experiences — and although Scribe’s first product is focused on Zoom, those experiences weren’t Zoom-related at all.

Instead, Siroker recalled starting to go deaf and then having an “epiphany” the first time he put in a hearing aid, as he recovered a sense he thought he’d lost.

“That really was the spark that got me thinking about other opportunities to augment things your body naturally fails at,” he said.

Siroker added that memory was an obvious candidate, particularly since he also has aphantasia — the inability to visualize mental images, which made it “hard to remember certain things.”

It may jog your own memory if I note that Siroker founded Optimizely with Pete Koomen in 2010, then stepped down from the CEO role in 2017, with the testing and personalization startup acquired by Episerver last year. (And now Episerver itself is rebranding as Optimizely.)

Fast-forward to the present day and Siroker is now CEO at Scribe, which is taking signups for its first product. That product integrates into Zoom meetings and transforms them into searchable, shareable transcripts.

Siroker demonstrated it for me during our Zoom call. Scribe appears in the meeting as an additional participant, recording video and audio while creating a real-time transcript. During or after the meeting, users can edit the transcript, watch or listen to the associated moment in the recording and highlight important points.

From a technological perspective, none of this feels like a huge breakthrough, but I was impressed by the seamlessness of the experience — just by adding an additional participant, I had a full recording and searchable transcript of our conversation that I could consult later, including while I was writing this story.

Although Scribe is recording the meeting, Siroker said he wants this to be more like a note-taking replacement than a tape recorder.

“Let’s say you and I were meeting and I came to that meeting with a pen and paper and I’m writing down what you’re saying,” he said. “That’s totally socially acceptable — in some ways, it’s flattering … If instead, I brought a tape recorder and plopped in front of you and hit record — you might actually have this experience — with some folks, that feels very different.”

The key, he argued, is that Scribe recordings and transcripts can be edited, and you can also turn individual components on and off at any time.

“This is not a permanent record,” he said. “This is a shared artifact that we all create as we have a meeting that — just like a Google Doc — you can go back and make changes.”

That said, it’s still possible that Scribe could record some embarrassing comments, and the recordings could eventually get meeting participants in trouble. (After all, leaked company meeting recordings have already prompted a number of news stories.) Siroker said he hopes that’s “not common,” but he also argued that it could create an increased sense of transparency and accountability if it happens occasionally.

Scribe has raised around $5 million in funding, across a round led by OpenAI CEO Sam Altman and another led by First Round Capital.

Siroker told me he sees Zoom as just the “beachhead” for Scribe’s ambitions. Next up, the company will be adding support for products like Google Meet and Microsoft Teams. Eventually, he hopes to build a new “hive mind” for organizations, where everyone is “smarter and better” because so many of their conversations and knowledge are now searchable.

“Where we go after that really depends on where we think we can have the biggest positive impact on people’s lives,” he said. “It’s harder to make a case for personal conversations you have with a spouse but … I think if you strike the right balance between value and privacy and control, you could really get people to adopt this in a way that actually is a win-win.”

And if Scribe actually achieves its mission of helping us to record and recall information in a wide variety of contexts, could that have an impact on our natural ability to remember things?

“Yes is the answer, and I think that’s okay,” he responded. “Your brain has limited energy … Remembering the things somebody said a few weeks ago is something a computer can do amazingly. Why waste your precious brain cycles doing that?”

Early Stage is the premier ‘how-to’ event for startup entrepreneurs and investors. You’ll hear first-hand how some of the most successful founders and VCs build their businesses, raise money and manage their portfolios. We’ll cover every aspect of company-building: Fundraising, recruiting, sales, product market fit, PR, marketing and brand building. Each session also has audience participation built-in – there’s ample time included for audience questions and discussion.

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A new auto-injecting pill might soon become a replacement for subcutaneous injection treatments.

The idea for this so-called robotic pill came out of a research project around eight years ago from InCube Labs — a life sciences lab operated by Rani Therapeutics Chairman and CEO Mir Imran, who has degrees in electrical and biomedical engineering from Rutgers University. A prominent figure in life sciences innovation, Imran has founded more than 20 medical device companies and helped develop the world’s first implantable cardiac defibrillator.

In working on the technology behind San Jose-based Rani Therapeutics, Imran and his team wanted to find a way to relieve some of the painful side effects of subcutaneous (or under-the-skin) injections, while also improving the treatment’s efficacy. “The technology itself started with a very simple thesis,” said Imran in an interview. “We thought, why can’t we create a pill that contains a biologic drug that you swallow, and once it gets to the intestine, it transforms itself and delivers a pain-free injection?”

Rani Therapeutics’ approach is based on inherent properties of the gastrointestinal tract. An injecting mechanism in their pill is surrounded by a pH-sensitive coating that dissolves as the capsule moves from a patient’s stomach to the small intestine. This helps ensure that the pill starts injecting the medicine in the right place at the right time. Once there, the reactants mix and produce carbon dioxide, which in turn inflates a small balloon that helps create a pressure difference to help inject the drug-loaded needles into the intestinal wall. “So it’s a really well-timed cascade of events that results in the delivery of this needle,” said Imran.

Despite its somewhat mechanical procedure, the pill itself contains no metal or springs, reducing the chance of an inflammatory response in the body. The needles and other components are instead made of injectable-grade polymers, that Imran said has been used in other medical devices as well. Delivering the injections to the upper part of the small intestine also carries little risk of infection, as the prevalence of stomach acid and bile from the liver prevent bacteria from readily growing there.

One of Imran’s priorities for the pill was to eliminate the painful side effects of subcutaneous injections. “It wouldn’t make sense to replace them with another painful injection,” he said. “But biology was on our side, because your intestines don’t have the kind of pain sensors your skin does.” What’s more, administering the injection into the highly vascularized wall of the small intestine actually allows the treatment to work more efficiently than when applied through subcutaneous injection, which typically deposits the treatment into fatty tissue.

Imran and his team have plans to use the pill for a variety of indications, including the growth hormone disorder acromegaly, diabetes and osteoporosis. In January 2020, their acromegaly treatment, Octreotide, demonstrated both safety and sustained bioavailability in primary clinical trials. They hope to pursue future clinical trials for other indications, but chose to prioritize acromegaly initially because of its well-established treatment drug but “very painful injection,” Imran said.

At the end of last year, Rani Therapeutics raised $69 million in new funding to help further develop and test their platform. “This will finance us for the next several years,” said Imran. “Our approach to the business is to make the technology very robust and manufacturable.”

Early Stage is the premier ‘how-to’ event for startup entrepreneurs and investors. You’ll hear first-hand how some of the most successful founders and VCs build their businesses, raise money and manage their portfolios. We’ll cover every aspect of company-building: Fundraising, recruiting, sales, product market fit, PR, marketing and brand building. Each session also has audience participation built-in – there’s ample time included for audience questions and discussion.

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Robotic process automation (RPA) is making a major impact across every industry. But many don’t know how common the technology is and may not realize that they are interacting with it regularly. RPA is a growing megatrend — by 2022, Gartner predicts that 90% of organizations globally will have adopted RPA and its received over $1.8 billion in investments in the past two years alone.

Due to the shift to remote work, companies across every industry have implemented some form of RPA to simplify their operations to deal with an influx of requests. For example, when major airlines were bombarded with cancellation requests at the onset of the pandemic, RPA became essential to their customer service strategy.

According to Forrester, one major airline had over 120,000 cancellations during the first few weeks of the pandemic. By utilizing RPA to handle the influx of cancellations, the airline was able to simplify its refund process and assist customers in a timely matter.

Delivering this type of streamlined cancellation process with such high demand would have been extremely challenging, if not impossible, without RPA technology.

The multitude of other RPA use cases that have popped up since COVID-19 have made it evident that RPA isn’t going away anytime soon. In fact, interest in the usage of RPA is at an unprecedented high. Gartner inquiries related to RPA increased over 1,000% during 2020 as companies continue to invest.

However, there’s one big issue that’s commonly overlooked when it comes to RPA — security. Like we’ve seen with other innovations, the security aspect of RPA isn’t implemented in the early stages of development — leaving organizations vulnerable to cybercriminals.

If the security vulnerabilities of RPA aren’t addressed quickly, there will be a string of significant RPA breaches in 2021. However, by realizing that these new “digital coworkers” have identities of their own, companies can secure RPA before they make the headlines as the latest major breach.

Understanding RPA’s digital identity

With RPA, digital workers are created to take over repetitive manual tasks that have been traditionally performed by humans. Their interaction directly with business applications mimics the way humans use credentials and privilege — ultimately giving the robot an identity of its own. An identity that is created and operates much faster than any human identity but doesn’t eat, sleep, take holidays, go on strike or even get paid.

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‍Eco, which has built out a digital global cryptocurrency platform, announced Friday that it has raised $26 million in a funding round led by a16z Crypto.

Founded in 2018, the SF-based startup’s platform is designed to be used as a payment tool around the world for daily-use transactions. The company emphasizes that it’s “not a bank, checking account, or credit card.”

“We’re building something better than all of those combined,” it said in a blog post. The company’s mission has also been described as an effort to use cryptocurrency as a way “to marry savings and spending,” according to this CoinList article.

Eco users can earn up to 5% annually on their deposits and get 5% cash back when transacting with merchants such as Amazon, Uber and others. Next up: The company says it will give its users the ability to pay bills, pay friends and more “all from the same, single wallet.” That same wallet, it says, rewards people every time they spend or save.

After a “successful” alpha test with millions of dollars deposited, the company’s Eco App is now available to the public.

A slew of other VC firms participated in Eco’s latest financing, including Founders Fund, Activant Capital, Slow Ventures, Coinbase Ventures, Tribe Capital, Valor Capital Group and more than one hundred other funds and angels. Expa and Pantera Capital co-led the company’s $8.5 million funding round.

CoinList co-founder Andy Bromberg stepped down from his role last fall to head up Eco. The startup was originally called Beam before rebranding to Eco “thanks to involvement by founding advisor, Garrett Camp, who held the Eco brand,” according to Coindesk. Camp is an Uber co-founder and Expa is his venture fund.

For a16z Crypto, leading the round is in line with its mission.

In a blog post co-written by Katie Haun and Arianna Simpson, the firm outlined why it’s pumped about Eco and its plans.

“One of the challenges in any new industry — crypto being no exception — is building things that are not just cool for the sake of cool, but that manage to reach and delight a broad set of users,” they wrote. “Technology is at its best when it’s improving the lives of people in tangible, concrete ways…At a16z Crypto, we are constantly on the lookout for paths to get cryptocurrency into the hands of the next billion people. How do we think that will happen? By helping them achieve what they already want to do: spend, save, and make money — and by focusing users on tangible benefits, not on the underlying technology.”

Eco is not the only crypto platform offering rewards to users. Lolli gives users free bitcoin or cash when they shop at over 1,000 top stores.

Early Stage is the premier “how-to” event for startup entrepreneurs and investors. You’ll hear firsthand how some of the most successful founders and VCs build their businesses, raise money and manage their portfolios. We’ll cover every aspect of company building: Fundraising, recruiting, sales, product-market fit, PR, marketing and brand building. Each session also has audience participation built-in — there’s ample time included for audience questions and discussion.

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Founders in the earliest stages of startup life face a hefty learning curve. Just some of the core competencies you need to lock down include how to raise VC funding, recruiting the right people, finding product-market fit and building a killer go-to-market team. The list goes on and on…and on. You’ll learn about all those topics and more at TechCrunch Early Stage Operations & Fundraising taking place on April 1-2. 

Do you science? Are you inspired to use biology as technology? If your entrepreneurial interests lean toward the scientific side of the startup equation, you don’t want to miss this special session — brought to you by Mayfield — at TC Early Stage 2021 on April 1-2.

Scientist Entrepreneurs — Scaling Breakout Engineering Biology Companies 

Arvind Gupta and Ursheet Parikh, early-stage investors, company builders and Mayfield partners, along with Po Bronson, NYT bestselling author and managing director of IndieBio, will discuss scaling startups and touch upon three seminal areas that influence trajectory: fundraising, hiring and product design. Their insights draw on their experience with companies including ingredients-as-service leader Geltor (which raised a $91 million Series B in 2020); CRISPR platform Mammoth Biosciences (its dream team includes co-founder and Nobel Laureate Jennifer Doudna); and Endpoint Health (started by GeneWEAVE’s founding team and former YC Bio Partner Diego Rey).

Whether you’re a biotech entrepreneur, a researcher or a scientist tackling the daunting challenges of human and planetary health, this session will help you build a stronger, more successful startup as you take your product to market.

Mayfield will follow up this session with even more content at Disrupt 2021 in September. These sessions will reveal company-building insights from entrepreneurs, investors, industry leaders and policymakers. Mayfield invests in exceptional people whose mission in life is to create a better world — not just for our generation  but for future generations as well. If you science, don’t miss your opportunity to learn from leading investors who have partnered with iconic biotech and health IT entrepreneurs — from Amgen and Genentech to Mammoth Biosciences.

Get your ticket for the April TC Early Stage event here. Or get a dual-event ticket for the April and July events for double the knowledge across operations, marketing, recruiting and fundraising — and save up to $100.

Is your company interested in sponsoring or exhibiting at Early Stage 2021 — Operations & Fundraising? Contact our sponsorship sales team by filling out this form.

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The Techstars Foundation recently announced a new program called Accelerate Equity.

We created the Techstars Foundation in 2015 to help make innovation and entrepreneurship more accessible and inclusive. Since then, the Techstars Foundation has been investing in and accelerating nonprofits that deliver scalable impact for underestimated entrepreneurs.

Through Accelerate Equity, the Techstars Foundation identifies early-stage nonprofits and ideas to empower and support underestimated entrepreneurs. Each non-profit has a significant nominating donor. We then call on the Techstars network to pitch in, provide mentorship, and add additional financial donations. The Techstars Foundation will add a 5% match to the total raised at the end of the calendar quarter.

Amy and I helped get this program started by nominating and underwriting initial grants to Grid 110, Sistahbiz, and HBCUvc. The Techstars Foundation added Knox St. Studios to the list.

Grid 110 – pathways to success for entrepreneurs in LAKnox St. Studios – building community wealth through entrepreneurship in North Carolina  Sistahbiz – membership organization for Black women entrepreneurs HBCUvc – directing how capital is formed and distributed to increase opportunities for Black and Latinx innovators

If you are interested in supporting any of these organizations, please click on the respective link above or reach out to the Techstars Foundation. Or, for the three I’m involved in, drop me an email also, and I’ll make an appropriate connection.

The post Techstars Foundation Accelerate Equity appeared first on Feld Thoughts.

Uber and OpenAI researchers say an advance in Go-Explore AI in beating Atari games could have applications for robotics and drug design.Read More